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Name:  Chi Wu (吳奇)

Born:  Mar, 1955, Anhui

Address:　Department of Chemical Physics University of Science and Technology of China, 230026 Hefei, P. R. China

Fax:  86-551-63606743

E-mail:  [email protected]

教育和研究背景

1995-now 188bet足球化(hua)學物理系(xi)客座教(jiao)授

2020-now  深圳大(da)學食品(pin)科學與加工中心(xin)主任(ren)、香港中文大(da)學偉倫化學榮休(xiu)講座教授

2010-2020 香(xiang)港(gang)中(zhong)文大學偉(wei)倫化學講座(zuo)教授  

研究興趣

他的(de)(de)(de)研(yan)(yan)究長于(yu)“集(ji)合成化學(xue)，高(gao)分(fen)(fen)(fen)子(zi)(zi)物理和分(fen)(fen)(fen)子(zi)(zi)生物之(zhi)成，設(she)計和執行決定(ding)性(xing)(xing)的(de)(de)(de)實驗來回答(da)一(yi)些與(yu)(yu)(yu)大(da)(da)(da)分(fen)(fen)(fen)子(zi)(zi)，生物以及膠體有關(guan)(guan)的(de)(de)(de)重要問題。”其(qi)中(zhong)包括，分(fen)(fen)(fen)子(zi)(zi)藥物非病毒(du)載體的(de)(de)(de)設(she)計與(yu)(yu)(yu)研(yan)(yan)發；與(yu)(yu)(yu)神(shen)經退化型疾病有關(guan)(guan)的(de)(de)(de)蛋白聚(ju)集(ji)的(de)(de)(de)初始成核過程；功能(neng)性(xing)(xing)大(da)(da)(da)分(fen)(fen)(fen)子(zi)(zi)的(de)(de)(de)設(she)計，合成和聚(ju)集(ji)；大(da)(da)(da)分(fen)(fen)(fen)子(zi)(zi)溶液和凝膠網絡的(de)(de)(de)動(dong)力學(xue)與(yu)(yu)(yu)結構(gou)；以及難解和特殊高(gao)分(fen)(fen)(fen)子(zi)(zi)的(de)(de)(de)分(fen)(fen)(fen)子(zi)(zi)特性(xing)(xing)。他近年的(de)(de)(de)研(yan)(yan)究興(xing)趣(qu)又(you)擴展到食(shi)品科學(xue)與(yu)(yu)(yu)加工，尤(you)其(qi)是大(da)(da)(da)豆(dou)蛋白和其(qi)它植(zhi)物大(da)(da)(da)分(fen)(fen)(fen)子(zi)(zi)的(de)(de)(de)精(jing)深加工。

在研項目

1. 創立利用高分子(zi)超濾(lv)來分離和表征構(gou)象和構(gou)筑不(bu)同的(de)鏈的(de)方法（2010-2013）國家自然(ran)科學基金(jin)

2. 研究利用自(zi)組(zu)裝介(jie)導大(da)分子聚合法制(zhi)備的多嵌段共聚物(wu)（2011-2014）國家自(zi)然科學基(ji)金 

專業活動及獲取獎項

2003年(nian)獲國家自然科學(xue)二等獎并當選為中(zhong)國科學(xue)院(yuan)(yuan)院(yuan)(yuan)士

2002年獲中(zhong)國科學院優(you)秀研究生導師獎

2000年獲(huo)香港裘槎基(ji)金會杰出研究獎(jiang)和中國科學院杰出青年科學家(jia)獎(jiang)

1999年獲中國化學會(hui)高(gao)分子年會(hui)特別邀請報告獎及被選(xuan)為美國物理學會Fellow

1997年(nian)獲“求是”杰出(chu)青年(nian)學者(zhe)獎

1996年(nian)獲國家杰出青(qing)年(nian)基金

1989年獲德國洪堡研究獎學金(jin)

1982年獲(huo)郭(guo)沫若獎學(xue)金(jin)

代表性著作

1. Chi Wu,Shuiqin Zhou,“light-scattering study of the phase transition of poly(N-isopropyl-acrylamide) in water: I.single chain”Macromolecule

　 -s,28,8381(1995)

2. Chi Wu, Shuiqin Zhou,“First Observation of the Molten Globule State of a Single Homopolymer Chain”,Physics Review Letters,77(14),3053

　  (1996)

3. Chi Wu,Xiaohui Wang,“Globule-to-coil transition of a single homopolymer chain in solution”,Physical Review Letters,80(18),4092(1998)

4. Chi Wu,Zuowei Xie,Guangzhao Zhang,Guofu Zi,Yingfeng Tu,Yali Yang,Ping Cai and Ting Nie,“Self-assembly assisted polymerization(SAAP):

　 approaching long multi-block  copolymers with an ordered chain sequence and controllable block length”,Chem.Commun,23,2898(2002)

5. Fan Jin,Chi Wu,“Observation of the first-order transition in ultra-filtration of flexible linear polymer chains”,Physical Review Letters,96,237801

　 (2006) 

6. Kejin Zhou,Yijie Lu,Junfang Li,Lei Shen, Guangzhao Zhang, Zuowei Xie and Chi Wu, “The coil-to-globule-to-coil transition of linear polymer ch

　 -ains in dilute aqueous solutions: Effect of intrachain hydrogen bonding”, Macromolecules, 41, 8927-8931 (2008)

7. Rui Deng,Yanan Yue,Fan Jin,Yangchao Chen,Hsiang-Fu Kung,Marie C.M.Lin,Chi Wu,“Revisit the complexation of PEI and  DNA — How to

　make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?”Journal of Controlled

　Release,140,40-46(2009)(Cover Story)

8. Hui Ge,Chi Wu,“Separation of linear and star chains by a nanopore”Macromolecules,43,8711-8713(2010) 

9. Yanan Yue,Fan Jin,Rui Deng,Jinge Cai,Yangchao Chen,Marie C.M.Lin,Hsiang-Fu Kung and Chi Wu,“Revisit complexation between DNA

　and polyethylenimine-Effect of uncomplexed chains free in the solution mixture on gene transfection”,Journal of  Controlled Release,155,

67–76(2011)

10. Chi Wu,“Why RNA and Protein Chains are Linear and not Colliding inside Nuclear Pores”,Macromolecules,45,4422-4424 (2012)